Table 1.

Crystal structures of vacuolar plasmepsins (P. falciparum unless noted otherwise) that are have been deposited in the Protein Data Bank by March 2011.

Protein	PDB code	Resol (Å)	Ligand	Year deposited	Reference	Remarks
PMI	3QRV	2.4	-	2011	[44]
	3QS1	3.1	KNI-10006	2011	[44]
PMII	1SME	2.7	Pepstatin A	1997	[39]
	1PFZ	1.85	-	1999	[35]	zymogen
	1LF2	1.8	RS370	2002	[28]
	1LF3	2.7	EH58	2002	[29]
	1LF4	1.9	-	2002	[29]
	1LEE	1.9	RS367	2002	[28]
	1M43	2.4	Pepstatin A	2002	-
	1ME6	2.7	Statine-based inhibitor (C25H47N3O6)	2004	[41]
	1XDH	1.7	Pepstatin A	2005	[81]
	1XE5	2.4	Pepstatin analogue (C29H47F6N5O9)	2005	[81]
	1XE6	2.8	Pepstatin analogue (C28H45F6N5O9)	2005	[81]
	2BJU	1.56	Achiral inhibitor (C37H44N4O3)	2005	[78]
	2IGX	1.70	Achiral inhibitor (C41H49N5O2)	2006	[79]
	2IGY	2.60	Achiral inhibitor (C35H48N4O)	2006	[79]
	1W6H	2.2	Inhibitor (C32H45BrN6O7), bulky P1 side chain	2006	[82]
	1W6I	2.7	Pepstatin A	2006	[82]
	2R9B	2.8	Reduced peptide inhibitor	2007	[58]
	3F9Q	1.9	-	2009	[64]	Re-refinement of 1LF4
HAP	3FNS	2.5	-	2009	[15]
	3FNT	3.3	Pepstatin A	2009	[15]
	3FNU	3.0	KNI-10006	2009	[15]
	3QVI	2.2	KNI-10395	2011	-
	3QVC	1.9	-	2011	-	zymogen
PMIV	1QS8	2.5	Pepstatin A	1999	[40]	(P. vivax)
	1MIQ	2.5	-	2002	[40]	zymogen (P. vivax)
	1LS5	2.8	Pepstatin A	2003	[29]
	2ANL	3.3	KNI-764	2006	[38]	P. malariae