Table 2.
Chemical formulas of the inhibitors bound to plasmepsins in the crystal structures of their complexes deposited in the PDB.
| No | Structure | Name | PDB |
|---|---|---|---|
| 1 |
|
Pepstatin A | 1XDH, 1W6I, 1M43, 1SME, 1QS8, 3FNT, 1LS5 |
| 2 |
|
Statine-based inhibitor | 1ME6 |
| 3 |
|
Pepstatin analogue | 1XE5 |
| 4 |
|
Pepstatin analogue | 1XE6 |
| 5 |
|
Inhibitor with bulky P1 side chain | 1W6H |
| 6 |
|
Peptide-based inhibitor | 2R9B |
| 7 |
|
RS367 | 1LEE |
| 8 |
|
RS370 | 1LF2 |
| 9 |
|
EH58 | 1LF3 |
| 10 |
|
Achiral inhibitor | 2BJU |
| 11 |
|
Achiral Inhibitor | 2IGX |
| 12 |
|
Achiral Inhibitor | 2IGY |
| 13 |
|
KNI-764 | 2ANL |
| 14 |
|
KNI-10006 | 3FNU, 3QS1 |
| 15 |
|
KNI-10395 | 3QVI |