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Action of cyclosporine A on AS-30D cell death produced by high concentrations of Zn2+ and selenite.
| Treatment (24 h) | 50 μM Se | 250 μM Zn | 500 μM Zn |
|---|---|---|---|
| none | 27 ± 3 | 31 ± 5 | 17 ± 6 |
| + CsA (1 μM) | 41 ± 1* | 55 ± 5** | 30 ± 6** |
The cell viability assayed by the trypan blue exclusion test is expressed in % to untreated control. Mean ±SE; n = 4 independent experiments; *P < 0.05 compared to selenite-treated control; **P < 0.05 compared to Zn(II)-treated control.
