Table 3.

Effects of high concentrations of Zn²⁺ and selenite on the uncoupled respiration of AS-30D cells. The rate of uncoupled respiration (in the presence of CCCP) of control cells is accepted as 100%.

Time	50 μM Se	250 μM Zn	500 μM Zn
3 h	86.4 ± 4.6*	48.4 ± 7.2*	28.3 ± 10.6*
24 h	n.d.	31.0 ± 5.0*	10.7 ± 0.5*
48 h	20.8 ± 6.5*	11.3 ± 1.3*	1.9 ± 0.3*

Rate of oxygen uptake is presented in percentage of the maximal (fully uncoupled) respiration of the control cells. Mean ± SE; n = 3 independent experiments; *P < 0.05 compared to untreated control. For other details, see Section 2; n.d., not determined.