Skip to main content
. 2011 May 17;301(2):E391–E401. doi: 10.1152/ajpendo.00164.2011

Fig. 5.

Fig. 5.

Deficiency of insulin secretion caused by STZ reverses the HFD-stimulated expression of long-chain acyl-coenzyme A (CoA) synthetases (ACSL) and changes in mitochondrial contents of long-chain acyl-CoAs, ADP, and ATP. A: expression of genes Acsl1 and Acsl5 in the livers of the mice described in Fig. 1 were determined by real-time PCR and normalized to 36B4. Mitochondrial contents of long-chain acyl CoAs (B) and ADP and ATP in liver (C) were quantified as detailed in materials and methods. Veh: saline. *P < 0.05 vs. ND and STZ + HFD.