Skip to main content
. 2011 May 10;301(2):E362–E369. doi: 10.1152/ajpendo.00696.2010

Fig. 3.

Fig. 3.

Phasic and tonic myometrial contractions in NP and P18 mice. Spontaneous phasic contractions (phasic tension in g/s; A) of NP (open bars) and P18 (closed bars) WT and db/+ mice. Peak (B) and steady-state (C) tension (g) developed in response to KCl (80 mM) in NP and P18 WT and db/+ mice on ND and HF mouse diets. Contractions were measured under control conditions (open bars) and following inhibition of Rho kinase with H1152 (1 μM, solid bars). Data are presented as means ± SE (*P < 0.05 vs. respective NP; †P < 0.05 vs. control). D: %steady-state contraction in response to KCl mediated by activation of Rho kinase in NP (open bars) and P18 (closed bars) mice. The percentage of KCl-induced contraction modulated by Rho kinase (ROCK) was assessed using the following formula: control contraction (g) minus contraction (g) in the presence of H1152 divided by control contraction (%ROCK-mediated contraction; means ± SE). *P < 0.05 vs. NP; †P < 0.05 vs. WT group.