Fig. 3.

Summary histogram of pAKT immunoreactivity (pAKT-IR) in the urothelium (A) and detrusor (B) of the urinary bladder of control and CYP-treated rats. Percent pAKT-IR above threshold in the urothelium following 48-h CYP treatment was significantly (**P ≤ 0.01) greater than control, 4-h, and chronic CYP treatment (A). Four-hour CYP treatment significantly increased percent pAKT-IR in the urothelium compared with chronic CYP treatment (A). B: percent pAKT-IR above threshold in the detrusor smooth muscle was significantly (*P ≤ 0.05) increased with 48-h CYP-treatment. Values are means ± SE (n = 4/group).