Table 1.

Evaluation of NK-1R expression, liver and body weight, liver-to-body weight ratio in the selected groups of animals

Groups	NK-1R Expression	Liver Weight, g	Body Weight, g	Liver/body weight × 100, %
WT normal mice (n = 84)	(−/+)	1.98 ± 0.05	26.3 ± 0.5	7.58 ± 0.16
NK-1R−/− normal mice (n = 79)	(−)	1.80 ± 0.05	28.3 ± 0.7	6.25 ± 0.18*
WT BDL mice (n = 41)	(++)	1.94 ± 0.06	21.92 ± 0.3†	8.84 ± 0.21†
NK-1R−/− BDL mice (n = 25)	(−)	2.07 ± 0.09	25.9 ± 0.7‡	7.96 ± 0.27‡

Data are means ± SE.

ND, not detectable; NK-1R, neurokinin-1 receptor.

^{*, †}P < 0.05 vs. the corresponding value of normal wild-type (WT) mice.

^‡P < 0.05 vs. the corresponding value of WT bile duct-ligated (BDL) mice.