Fig. 4.
Ghrelin-positive X/A-like cells in the gastric oxyntic mucosa express the sst2a receptor in naive rats. Paraffin-embedded gastric corpus sections of ad libitum-fed rats were processed for immunofluorescent double labeling. Confocal microscopy shows the localization of sst2a-immunopositive cells throughout the gastric oxyntic mucosa (A, red), whereas ghrelin-positive cells are localized mostly in the middle and the lower part of the glands (B, green). The picture in C and the higher magnification (D) show that ghrelin-positive cells express the sst2a receptor (arrow). Lu, lumen; Mu, mucosa; Submu, submucosa.