Skip to main content
. 2011 Jun 2;301(2):G239–G248. doi: 10.1152/ajpgi.00018.2011

Table 1.

Time course of changes in plasma levels of intestinal hormones after abdominal surgery in rats

Hormone Plasma Level, pg/ml
GLP-1
PYY
PP
Time point, h Sham Surgery Sham Surgery Sham Surgery
0 39.6 ± 3.4 42.3 ± 3.5 75.0 ± 7.4 78.1 ± 13.5 66.0 ± 9.7 80.0 ± 10.5
2 37.6 ± 2.6 36.8 ± 3.7 65.0 ± 7.0 41.9 ± 3.6* 55.5 ± 8.4 50.4 ± 7.6
5 37.4 ± 4.9 39.9 ± 2.5 73.4 ± 13.8 51.8 ± 4.6 64.2 ± 11.4 97.3 ± 8.1*
24 37.2 ± 5.3 27.8 ± 1.8 110.4 ± 45.2 113.2 ± 26.1 105.1 ± 10.2 100.9 ± 18.2

Rats were fasted overnight and underwent abdominal surgery consisting of laparotomy and cecal palpation (1 min) or anesthesia alone (sham) and levels of glucagon-like peptide 1 (GLP-1), peptide YY (PYY), and pancreatic polypeptide (PP) were assessed before, and at 2, 5, 7, and 24 h postsurgery. Data are presented as means ± SE of 5 rats/group;

*

P < 0.05 vs. sham.