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a) Schematic representation of cationic nanoparticle, showing the interaction between the trimethylammonium sidechains and the anionic DNA. b) Relative sizes of the 37-mer DNA duplex (extended conformation) and particle. c) Representative acrylamide gel electrophoresis of the RNA products. Lanes are numbered with colloid (nanoparticle) equivalents used in each assay. d) The amount of RNA detected relative to levels produced in the absence of colloids (100% transcription).
