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. 2011 May 13;301(2):L161–L170. doi: 10.1152/ajplung.00073.2011

Fig. 8.

Fig. 8.

Effect of PDE2A knockdown with Ad.PDE2A-shRNA infection (n = 4) vs. control infection with Ad.Neg-shRNA (n = 4) in mice subjected to 1 day of LPS followed by HVT ventilation on lung cAMP concentration (A) and lung cGMP concentration (B). To examine the contribution of adenoviral infection, the effect of HVT ventilation 1 day after IT LPS in the absence of adenoviral infection on cyclic nucleotide concentrations is shown (n = 3) along with a group of IT water, no HVT controls (n = 3). Values are means ± SE. *P < 0.002 vs. Ad.Neg-shRNA group.