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. 2011 May 13;301(2):L187–L196. doi: 10.1152/ajplung.00082.2011

Fig. 2.

Fig. 2.

Evaluation of small interfering RNA (siRNA) stability and specific target gene inhibition via intrapulmonary injection. A: a Cy3-conjugated siRNA to cyclophilin B (siGLO) was injected into left lung of neonatal mouse, and a fluorescent micrograph was obtained at 24 and 72 h after injections. Arrows indicate injection sites. Inset: focused view of injected area. B: Western blots of C/EBPα protein levels after intrapulmonary injection. Blots represent results from 3 experiments. Only 1 of the 2 samples originally loaded on the gel is shown. Inadequately loaded lanes were omitted (white spaces). C: densitometric evaluation of 42-kDa C/EBPα protein. Values are means ± SE of 3 mice in each group. Open bars, injected left lungs; solid bars, corresponding noninjected right lungs. *P < 0.05 vs. noninjected lungs.