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Example of immunoreactivity of sera obtained from a PD patient and a control healthy individual with recombinant synuclein proteins. A membrane with full-length recombinant synucleins (Ponceau-S staining is shown in the top panel) was subsequently probed with PD serum GRSPD4 (middle panel) and control serum [c_3880] (bottom panel). α-S: α-synuclein, α-SA53T: α-synuclein with A53T mutation, β-S: β-synuclein, γ-S: γ-synuclein.
