Contractile responses to uridine adenosine tetraphosphate (Up4A) and phenylephrine (PE) are augmented in renal arteries (RA) but not pulmonary arteries (PA)from DOCA-salt hypertensive rats. Concentration-response curves for Up4A (A, B) and PE (C, D) in RA (A, C) and PA (B, D) arterial rings obtained from DOCA-salt (DOCA) and normotensive control [uninephrectomized (Uni)] rats are shown. Data are means ± SE from 6 to 8 experiments; the SE is included only when it exceeds the dimension of the symbol used. *P < 0.05, DOCA vs. Uni.