Table 1.

Mechanical and geometry results of aortas from apoE^−/− and apoE^−/−xTg^SMC-Cat mice with and without ANG II treatment

	ANG II	λz	d, mm	B, mm	H, μm	O.A., °
apoE−/−	−	1.48 ± 0.005	1.37 ± 0.03	0.343 ± 0.02	89 ± 2.1	130 ± 1
	+	1.38 ± 0.04*	1.39 ± 0.08	0.342 ± 0.06	89 ± 1.9	198 ± 8*
apoE−/−xTgSMC-Cat	−	1.26 ± 0.008*	1.16 ± 0.01*†	0.347 ± 0.005	98 ± 2.1*†	130 ± 8†
	+	1.23 ± 0.05*	–	–	88 ± 1.6‡	130 ± 5†

Values are means ± SE. Stretch ratio and loaded diameter data were acquired during isolated aortic inflation. Unloaded morphology was acquired from histological analysis of bisected aortic rings used in opening angle (O.A.) measurement. apoE^−/−, apolipoprotein E-deficient mice; apoE^−/−xTg^SMC-Cat, apoE^−/− mice that overexpress catalase in vascular smooth muscle cells; λ_z, axial stretch ratio (l/L), where l is loaded length and L is unloaded length; d, ex vivo loaded diameter; B, unloaded outer radius; H, unloaded thickness.

^*P < 0.05 vs. apoE^−/−.

^†P < 0.05 vs. apoE^−/− + ANG II.

^‡P < 0.05 vs. apoE^−/−xTg^SMC-Cat.