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A–F: concentration-response curves to phenylephrine (PE, 10−10 to 10−5 mmol/l) in the carotid artery of female and male knockout (KO), wild-type (WT), maternally derived heterozygous (KOM), and paternally derived heterozygous (KOP) offspring at 7, 14, and 21 wk of age (female, n = 6–8/age group; male, n = 6–10/age group).
