Table 1.

Changes in MAP, renal SND, and splenic SND to sciatic nerve stimulation before and after RVLM Kyn (2.7 and 5.4 nmol) microinjections

	n	Stimulation Before RVLM Kyn	Stimulation After RVLM Kyn
2.7 nmol RVLM Kyn
ΔMAP, mmHg	3	+26 ± 2	+5 ± 2
ΔRenal SND, %	3	+76 ± 10	−8 ± 10
ΔSplenic SND, %	2	+88 ± 29	+7 ± 2
5.4 nmol RVLM Kyn
ΔMAP, mmHg	3	+21 ± 1	+6 ± 5
ΔRenal SND, %	3	+45 ± 10	−27 ± 5
ΔSplenic SND, %	2	+56 ± 18	+14 ± 26

Values are means ± SE;

n, no. of rats. RVLM, rostral ventrolateral medulla; Kyn, kynurenic acid; Δ, change; MAP, mean arterial pressure; SND, sympathetic nerve discharge.