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. 2000 May 15;105(10):1331–1332. doi: 10.1172/JCI10072

Figure 1.

Figure 1

Proposed mechanisms for the pathogenesis of inflammation in asthma. Whereas mast cells are directly stimulated by allergen-specific IgEs and provoke the early phase of asthmatic bronchoconstriction, eosinophils activate later inflammatory responses.