Table 1.
Demographic, baseline clinical characteristics and patterns of use of the patients randomized to placebo and dronabinol (N=156)*
| Characteristic | Placebo ** (n=77) |
Dronabinol (n=79) |
|---|---|---|
| Demographic characteristics | mean (SD) or n (%) | |
| Age (years) | 38.4 (9.2) | 36.9 (10.8) |
| Male | 61 (79.2%) | 67 (84.8%) |
| Race/Ethnicity*** | ||
| Hispanic | 16 (20.8%) | 22 (27.9%) |
| Black | 12 (15.6%) | 19 (24.1%) |
| White | 43 (55.8%) | 32 (40.5%) |
| Other | 6 (7.8%) | 6 (7.6%) |
| Education | ||
| High school | 19 (25.0%) | 24 (30.8%) |
| Some college | 17 (22.4%) | 15 (19.2%) |
| College | 27 (35.5%) | 29 (37.2%) |
| Graduate school | 13 (17.1%) | 10 (12.8%) |
| Employment status | ||
| Full-time | 49 (64.5) | 45 (57.0%) |
| Part-time | 11 (14.5) | 10 (12.7%) |
| Unemployed/others | 16 (21.1) | 24 (30.4%) |
| Currently married | 25 (32.5) | 24 (30.4%) |
| Clinical characteristics | ||
| Marijuana Withdrawal Checklist | ||
| Withdrawal Discomfort Score (WDS)-10 | 8.0 (5.4) | 7.1 (4.7) |
| Total | 14.6 (0.9) | 13.2 (9.0) |
| Marijuana Craving Questionnaire (MCQ) | ||
| MCQ: Compulsion | 3.5 (1.3) | 3.4 (1.2) |
| MCQ: Emotion | 4.5 (1.5) | 5.0 (1.4) |
| MCQ: Expectancy | 4.0 (1.3) | 4.2 (1.5) |
| MCQ: Purposefulness | 4.4 (1.6) | 4.5 (1.3) |
| MCQ: Total score | 4.0 (1.0) | 4.1 (1.0) |
| Hamilton-Anxiety | 4.7 (3.9) | 4.5 (3.8) |
| Hamilton-Depression (21-item) | 5.3 (3.5) | 5.3 (4.1) |
| Patterns of drug use | ||
| Age at first use | 15.4 (3.0) | 15.6 (4.0) |
| Age at regular use | 18.6 (5.2) | 18.6 (5.0) |
| median (IQR) | ||
| Days of use in last 7 days | 7 (7-7) | 7 (7-7) |
| Days of use in last 30 days | 30 (29-30) | 30 (29-30) |
| Amount spent per using day ($) | 5 (3-10) | 5 (3-10) |
| Amount per using day (g) | 0.5 (0.3-0.9) | 0.6 (0.4-0.9) |
*
Frequencies may not sum to N=156 due to missing values. Two patients did not report their education, and one patient did not report his employment status. Percentages may not add up to 100 due to rounding.
**
There were no statistically significant differences except MCQ: Emotion was p=.05
***
Participants classified their race based on options defined by the investigator