Table 5.
Incidence of living donor renal transplant recipients with ACR* at mean follow-up of 493 days
Alemtuzumab induction | Historical control | p-value | |
---|---|---|---|
Recipients | 205 | 47 | |
Cumulative recipients with ACR* at | |||
≤1 month** | 1.5% (3) | 12.8% (6) | p < 0.05 |
≤2 months | 1.5% (3) | 12.8% (6) | p < 0.05 |
≤3 months | 2.0% (4) | 12.8% (6) | p < 0.05 |
≤4 months | 2.4% (5) | 17.0% (8) | p < 0.05 |
≤6 months | 2.9% (6) | 17.0% (8) | p < 0.05 |
≤12 months | 6.8% (14) | 17.0% (8) | p = 0.047 |
At mean follow-up of 493 days, cumulative recipients with ACR were | 10.7% (22) | 21.3% (10) | p < 0.05 |
ACR recipients with >1 ACR episode | 45.5% (10) | 50.0% (5) | – |
Weaning attempted | 57.0% (118) | – | |
Preweaning ACR incidence | 4.3% (9) | – | |
Postweaning ACR incidence | 6.3% (13) | – |
All ACR were biopsy proven.