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Diabetes impairs sensory nerve fiber function. A–E: force stimulus response curves in C-fibers (5–200 mN, 10 s each, 1-min interstimulus interval; A) and SA Aβ-fiber responses (B), RA Aβ-fiber responses (C), AM fiber responses (D), and D-hair fiber responses (E) to increasing mechanical stimuli in diabetic versus nondiabetic mice. AP, action potential. *P < 0.05 and **P < 0.01 by two-way ANOVA followed by a post hoc Bonferroni t-test.
