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. 2011 Aug 11;7(8):e1002172. doi: 10.1371/journal.ppat.1002172

Table 2. Neutralization capacity and reactivity pattern of recombinantly expressed human monoclonal antibodies.

50% neutralization activity (µg/ml) a
Group and Clone original IgG isotype fibroblasts endoth. cell epithel. cell dendritic cell reactivity with domain I peptideb reactivity with domain II peptideb
SM10 IgG3/κ 0.1 0,35 1,0 n.d. + -
1G2 IgG3/λ 0.2 0,5 1,5 n.d. + -
SM12 IgG1/κ 0.4 0,67 n.d. n.d. + -
2C2 IgG1/κ 0.6 1,8 n.d. n.d. + -
SM1-6 IgG1/λ 1.3 1.3 0.3 1.3 - +
SM3-1 IgG1/λ 1.2 1.0 0.4 1.0 - +
SM4-5 IgG1/λ 0.6 0.8 0.9 0.4 - +
SM5-1 IgG1/λ 0.3 0.2 0.2 0.3 - +
SM6-5 IgG1/λ 0.5 0.4 0.3 0.5 - +
SM11-17 IgG1/λ 1.0 1.0 0.3 1.3 - +
a

every antibody was tested at least 3 times with similar results.

b

tested by immunofluorescence on transiently transfected Cos7 cells.