Table 2.
Characteristics, presentations, and outcome of patients with sinonasal moderately differentiated (MDNEC) and poorly differentiated (PDNEC) neuroendocrine carcinoma
| Characteristic | MDNEC | PDNEC |
|---|---|---|
| Demographics | ||
| Age at presentation | 47.6 (22-67) | 50 (24-78) |
| M:F ratio | 5:2 | 6:7 |
| Major Presenting Symptoms | ||
| Congestion/Sinusitis | 3 (43%) | 7 (54%) |
| Epistaxis | 3 (43%) | 3 (23%) |
| Hearing loss | 1 (14%) | 0 |
| Neck mass | 0 | 2 (15%) |
| Stage | ||
| I | 1 (14%) | 0 |
| II | 0 | 2 (15%) |
| III | 0 | 1 (8%) |
| IV | 5 (71%) | 9 (69%) |
| DFS | ||
| Ch + RT | 11 (mon) | 7.6 (mon) |
| RT + Surgery | 63 (mon) | 16.0 (mon) |
• Ch: Chemotherapy
• MDNEC: Moderately differentiated
• PDNEC: Poorly differentiated
• RT: Radiotherapy