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. 2011 Aug 11;6(8):e22889. doi: 10.1371/journal.pone.0022889

Figure 6. Archaeosome encapsulated Rv3619c offers protection against M.tb infection in BALB/c mice.

Figure 6

Mycobacterial load, in the lungs (A) and spleens (B) of vaccinated mice, belonging to various groups of animals, was enumerated by plating tissue homogenates of lungs and spleens of vaccinated mice followed by counting the numbers of colony-forming units (CFUs) at 4 and 8 weeks post challenge following method as described in methodology section of the text. The data were expressed as means of three determinants ± S.D. and are representative of 4 independent experiments. Statistical analysis was performed by ANOVA (analysis of variance) using Holm-Sidak method; p<0.01(**), p<0.001(***).