Table 4. Continuous renal replacement therapy and outcomes.
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Mean ± SD | |
Type | |||||||
CVVH or CVVHDF | CVVH | CVVH | CVVHDF | CVVH | CVVHDF | CVVHDF | - |
Therapy parameters | |||||||
Blood flow rate (ml/min) | 200 | 180 | 150 | 200 | 180 | 250 | 193±33 |
Effluent rate (ml/kg/h) | 34 | 33 | 39 | 22 | 38 | 36 | 34±6 |
Dialysate rate (ml/h) | 0 | 0 | 2500 | 0 | 2000 | 500 | 1250±1215 |
Replacement fluid rate (ml/h) | 1600 | 2500 | 2000 | 2500 | 2500 | 2800 | 2317±436 |
Filtration fraction (%) | 13 | 30 | 22 | 29 | 17 | 19 | 22±7 |
Initial fluid removal (ml/h) | 0 | 50 | 0 | 0 | 100 | 0 | 25±42 |
Length (days) | 5 | 12 | 15 | 1 | 3 | 5 | 7±5 |
Metformin clearance | |||||||
Rate of elimination (%/h) | 2.7 | 4.0 | 1.5 | 1.6 | 2.1 | 2.3 | 2.4±0.9 |
Outcomes | |||||||
ICU length of stay (days) | 11 | 26 | 17 | 8 | 22 | 9 | 16±7 |
Survival to discharge | Yes | Yes | Yes | Yes | Yes | Yes | - |
Discharge at home | Yes | Yes | Yes | Yes | Yes | Yes | - |
CVVH, continuous venovenous hemofiltration; CVVHDF, continuous venovenous hemodiafiltration.