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. 2011 Aug 11;7(8):e1002152. doi: 10.1371/journal.pcbi.1002152

Figure 5. Tunnels from the CYP2C9 buried active site to the protein surface.

Figure 5

(A) Cartoon representation of all tunnels that were observed to open during the atomic-resolution simulations, labeled according to the nomenclature of Cojocaru et al. [20]. The percentage of trajectory frames in which different channels were open (the smallest radius along the tunnel >1.2 Å) is shown for the models 1R9O1, 1R9OH1 (B), and 1R9O2, 1R9OH2 (C). The colors of the bars correspond to the colors assigned to each tunnel in (A).