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. 2011 Aug 11;6(8):e23452. doi: 10.1371/journal.pone.0023452

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Peng et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The negative log10 p values derived from t-tests were plotted against the average intensity levels for (A) genes located within and (B) outside the amplified regions. The spline curves were fit to extract the main trend of the data.