Table I.
Baseline | Shock | Post- Resuscitation |
|
---|---|---|---|
Enzymatic Activity (R) | 0.78 (±0.14) | 1.62 (±0.10)* | 1.97 (±0.10)*# |
Split Point (SP) | 0.72 (±0.13) | 1.30 (±0.11)* | 1.70 (±0.12)*# |
Thrombin Generation (Delta) | 0.07 (±0.03) | 0.32 (±0.11)* | 0.27 (±0.05)* |
Clot Formation (K) | 0.87 (±0.07) | 0.80 (±0.00) | 0.83 (±0.03) |
Fibrin Cross-linking (Angle) | 81.8 (±1.42) | 82.65 (±0.46) | 82.07 (±0.35) |
Platelet-Fibrin Interaction (MA) | 70.67 (±2.91) | 73.93 (±0.81) | 70.63 (±0.75) |
Clot Strength (G) | 12.75 (±3.48) | 13.68 (±1.59) | 12.22 (±1.06) |
Percent Lysis (LY30) | 0.15 (±0.13) | 1.03 (±0.66) | 1.40 (±1.15) |
R (min), SP (min), Delta (min), K (min), Angle (degrees), MA (mm), G (dynes/cm2), and EPL (%). Data are reported as mean ± standard deviation. These data show that coagulation factor function was significantly impaired in the early stages of trauma/hemorrhagic shock. TEG R, SP, and delta values were significantly increased from baseline to shock. No significant changes were found in K, angle, MA, G, and LY30 values. Significant data measured from baseline are labeled (*) with p-values <0.0001. Significant data measured from shock are labeled (#) with p-values <0.05.