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All male mice exhibited similar acquisition performance during spatial training (eight training trials) of the Morris water maze task. (a) Mean latency (sec) and (b) swim velocity (cm/sec) decreased across training trials, indicating the acquisition of the spatial memory task by all mice. Mice received an injection of cocaine (0 or 2.5 mg/kg) immediately, 1, 2, or 4 hr after trial 8. *Indicates p<0.05 when compared to swim trial 1.
