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Statistical parametric maps (SPMs) showing significant negative correlations between maternal age at birth and brain metabolism in NL MH from analysis of size-matched, demographically balanced groups (n=24 subjects/group), correcting for subjects’ age. Areas of maternal age-related hypometabolism are represented on color-coded scale reflecting Z scores between 0 and 3 (P<0.001, uncorrected). SPMs are displayed onto the axial views of a standard, spatially normalized MRI.
