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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Thromb Haemost. 2011 Aug;9(8):1562–1571. doi: 10.1111/j.1538-7836.2011.04394.x

Fig. 1.

Fig. 1

Heat exposure negatively regulated thrombin-induced αIIbβ3 activation. WPs were incubated at 37°, 38.5°, 40°, 41° or 42°C for 10 minutes and then stimulated with thrombin (0.05 U/ml) for 5 minutes. Analysis of PAC-1 and fibrinogen binding were performed by flow cytometry (n=6). *P < 0.05 vs. unstimulated control; #P < 0.05 vs. thrombin at 37°C.