FIG. 5.

Deltamethrin activates caspase-12 without altering the function of mitochondria. Western blot analysis of cytochrome c with α-tubulin immunoblot as loading control (A). Representative blots are presented and data are expressed as relative pixel density in bar graphs (B and C). Effects of deltamethrin on mitochondrial membrane potential at 24 (D) and 48 h (E). Activation of caspase-12 at 12 (F) and 24 h (G) after deltamethrin exposure. The values represent mean ± SEM from at least three individual experiments, each performed in triplicate. Data are expressed as percentage of vehicle control. * indicates significantly different from control (p < 0.05).