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. 2011 Aug 3;4(Suppl 1):S7. doi: 10.1186/1756-6614-4-S1-S7

Table 2.

Uptake of iodothyronines by TH transporters expressed at the blood-brain barrier. The levels of TH transport are indicated as follows: +++ high uptake rate, ++ modest uptake rate, and + low uptake rate; n.d., not determined.

Protein Iodothyronines Species References
3,3`-T 2 T 3 rT 3 T 4
MCT8 +/+ +++/+++ +/++ ++/++ human/rat [14,86]
OATP1C1 n.d. + +++ +++ human, rat, mouse [37-39]
LAT1 +++ ++ ++ + human [43]
LAT2 +++ ++ ++ + mouse [43]