Table 3.

Clinical Investigation Results

Patient	Age at Study	Motor				Sensory				Electromyography	Sural Nerve Biopsy	Muscle Biopsy
		Right Peroneal		Right Tibial		Right Sural		Right Sup Peroneal
		Amplitude (mV)	Velocity (m/s)	Amplitude (mV)	Velocity (m/s)	Pk-Pk (μV)	Velocity (m/s)	Pk-Pk (μV)	Velocity (m/s)
II 10	29	–	–	3.85	46	20	39	–	–	chronic denervation	–	–
II 13	31	–	–	4.3	51	12	41	–	–	central neuronal atrophy	–	severe connective tissue replacement
II 15	36	normal	normal	normal	normal	normal	normal	normal	normal	–	indolent axon degenerative process with some evidence of fiber regeneration consistent with a diagnosis of HMSN type 2	–
III 4	25	2.0	56.6	8.9	–	20.3	42.9	13.3	45.5	normal	–	–
III 14	28	5.4	44.2	7.1	39.6	8.6	37.7	7.8	40	vastus medialis MUPs enlarged otherwise normal	–	–
III 17	20	normal	normal	normal	normal	normal	normal	normal	normal	–	–	–
III 18	22	2.9	44	11.5	–	7	28	15	35	mild degree of large fiber axonal sensory motor peripheral neuropathy	–	–
III 21	2	normal	normal	normal	normal	normal	normal	normal	normal	interference pattern nonspecifically abnormal, occasional units up to 6 mV	–	–
IV 7	5	not performed	not performed	not performed	not performed	not performed	not performed	not performed	not performed	–	–	atrophic fibers consistent with chronic partial denervation