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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Kidney Int. 2011 Feb 2;79(10):1090–1098. doi: 10.1038/ki.2010.544

Figure 5. FTY720 reduces albuminuria independent of sphingosine 1-phosphate 3 receptor (S1P3R) effects.

Figure 5

Urine collections were obtained for measurement of urinary albumin excretion (UAE) at week 4 in S1P3+/+ (wild type, WT) and S1P3–/– mice after streptozotocin (STZ)-induced diabetes. Open bars, control group; black bars, vehicle-treated diabetes group; and gray bar, diabetes group treated with FTY720 (0.3 mg/kg, oral gavage). Data are means ± s.e.m. *P < 0.05 compared with control; +P < 0.05 compared with vehicle-treated diabetes group. Blood glucose (BG) values are shown below the bars for each group.