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. 2007 Feb 5;2:9–18.

Figure 1.

Figure 1

CsA suppresses HCV genome replication. (A) HCV RNA was quantified in total RNA isolated from HCV replicon-bearing cells treated with various concentrations of CsA, FK506, or IFNα for 7 days. The amount of HCV RNA per 1 pg total RNA was plotted against the concentration of CsA (μg/ml), FK506 (μg/ml), or IFNα (× 100 IU/ml). (B) The expression of HCV NS5A and protein disulfide isomerase (PDI) as a cellular protein was examined in the HCV replicon-bearing cells treated without (control) or with 100 IU/ml IFNα, 1_ μg/ml CsA, or 1_ μg/ml FK506 for 7 days.