Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Verification of PS1 in cells. (A) Schematic of PS1 showing proposed membrane topology and relative locations of the mutations (circles) chosen for this study. Critical aspartates are denoted by a star. Average age at onset is indicated in parentheses. (B) Western blot showing relative expression levels of the PS1 variants upon transient transfection into DKO cells.
