Table 1.

Clinical trials utilizing hydrochloroquine to modulate autophagy in cancer therapy

Clinical trials	Principal investigator, lead institution
HCQ and bortezomib in relapsed or refractory multiple myeloma (NCT00568880)	Stadtmauer, University of Pennsylvania (UPenn)
HCQ, RT and temozolomide in patients with glioblastoma multiforme (NCT00486603)	Rosenfeld, NCI/UPenn/Multiple Institutes
Ixabepilone and HCQ in metastatic breast cancer (NCT00765765)	Karantza-Wadsworth, Cancer Institute of New Jersey (CINJ)
HCQ, carboplatin, paclitaxel and bevacizumab in advanced lung cancer (NCT00728845)	Aisner, CINJ
HCQ in patients with PSA progression after local therapy for prostate cancer (NCT00726596)	Stein, CINJ