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Immunolocalization of aquaporin 4 (AQP 4) around blood vessels. (A, B) There is prominent AQP4 immunoreactivity (IR) around blood vessels affected by cerebral amyloid angiopathy (CAA) in Alzheimer disease (AD) cases. (C) Although not as prominent or “condensed,” is also present around blood vessels in AD without cerebral amyloid angiopathy (CAA). (Original magnification: 40x).
