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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2010 Dec;69(12):1201–1209. doi: 10.1097/NEN.0b013e3181fd252c

Fig. 7.

Fig. 7

Double labeling of aquaporin 4 (AQP 4) (purple) and glial fibrillary acidic protein (GFAP) (brown) in Alzheimer disease (AD) + cerebral amyloid angiopathy (CAA) cases. (A-C) AQP4 immunoreactivity (IR) colocalizes with GFAP+ astrocytes in a plaque-like distribution, consistent with senile plaques (A, B). Not all astrocytes have associated AQP4 IR, particularly in regions with few or no associated senile plaques (C). (Original magnifications: A, C, 10x; B, 20x).