Table 1.

Estimated Prevalence of AAT Genotypes in Ireland

Genotype	Prevalence [%, 95% CI]	Numbers in Ireland
MS	1/10 [10.00%, 9.70 - 10.30%]	423,947
MZ	1/25 [4.03%, 3.97 - 4.09%]	170,832
SS	1/341 [0.29%, 0.20 - 0.40%]	12,409
SZ	1/424 [0.24%, 0.23 - 0.25%]	10,001
ZZ	1/2,104 [0.05%, 0.04 - 0.06%]	2,015

Data from the Trinity Biobank presented as prevalence [% of total population, 95% confidence interval (CI)]. These figures are based on an Irish population of 4.24 million in the Republic of Ireland (www.cso.ie).