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Mice received intranasal instillations of saline or; 6.25 µg, 25 µg, 100 µg of MBS or; 6.25 µg, 25 µg, 100 µg of MSS, once daily, starting on day 0, for 3 consecutive days in a week, during 3 weeks. Mice were euthanized on day 20, 4 days after last archaea instillation.
