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. 2011 Aug 12;6(8):e23326. doi: 10.1371/journal.pone.0023326

Figure 4. Dominance of CD4+ T lymphocytes and CD19+ B lymphocytes in BALF of mice instilled with archaeal species.

Figure 4

The numbers of CD4+ T cells, CD8+ T cells and CD19+ B cells were analyzed in BALF of mice exposed for 3 weeks to 6.25, 25 and 100 µg of A) MBS or B) MSS. Compared to MBS, MSS induced strong CD4+ helper T cell and CD19+ B cell responses in the airways, which plateaued from the lowest dose instilled. Results are expressed as median ± interquartile intervals. Letters a and b represent statistical differences between treatment regimens within a same cell type. Six mice per group were analyzed. p<0.05.