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. 2011 Aug 12;6(8):e23326. doi: 10.1371/journal.pone.0023326

Table 1. Histopathological alterations of mice lungs exposed to MBS or MSS.

Saline MBS MSS
Criteria 6.25 µg 25 µg 100 µg 6.25 µg 25 µg 100 µg
Perivascular infiltration of mononuclear cell 0 1 2 3a 2 3 4a
Perivascular infiltration of granulocytes 0 0 0 0 1.5 0 0
Peribronchial infiltration of mononuclear cell 0 0a 1a 0a 1b 1b 1b
Thickening of alveolar septa 0 1a 1a 2a 2b 2b 3b
Macrophage accumulation 0 0.5 1.5 2a 1.5 1 2a

Results are expressed as median scores for each group, graded on a scale from 0 (no alteration) to 5 (severe alterations). Letters represent statistical differences between each dose of MBS and MSS within a same criteria. Six mice per group were analyzed. p<0.05.