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Three-pulse ESEEM and field-swept echo detected spectra of the nonlabeled and 15N-labeled Aβ(1–16) analogues mixed with an equimolar amount of Cu(II) at 2800 G at pH 7.4. The decrease in the 14N-ESEEM intensity below 8 MHz is more prominent when His6 or His14 is enriched with 15N. On the other hand, the 1H-ESEEM intensity of each spectrum is essentially identical.
