FIG. 7.

Images A-D are of a 20-year-old patient with drusen. Parental examination revealed no abnormalities. On FAF we see uniform macular fluorescence except for some focal regions of hyperfluorescence extending from the fovea to the temporal macula (images A+B). These discrete yellowish subretinal lesions can be seen on fundus photography also. On SD-OCT (image D), corresponding to the white dashed line in image A, we see these lesions as echolucent elevations of the RPE. The ISOS appears reasonably intact in the regions overlying these lesions. Images E-H are of a patient with pattern dystrophy. On AF we see punctate regions of discrete hyperfluorescence in the central macula (images E+F). These regions are also seen on fundus photography (image G). On SD-OCT (image H), the most striking abnormality is the loss of ISOS junction centrally (white double headed arrow). The RPE demonstrates few focal elevations. 152×106mm (300 × 300 DPI)