Figure 10.

Patients with a high number of CD34- and nestin immunopositive blood vessels also show an increased expression of VEGF and albumin positive cells in the basal ganglia (top, ‘high angiogenic index’). Representative bright-field photomicrographs in the putamen from cases with a ‘high angiogenic index’ (A, C, E and G) or a ‘low angiogenic index’ (B, D, F and H) show the expression of all markers under investigation: CD34 (A and B), nestin (C and D), VEGF (E and F), and albumin (G and H). Arrowhead in (E) shows punctate expression of VEGF at the border of a blood vessel. Scale bar = 25 μm.