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Effect of dual targeting of endothelial cells and pericytes on tumor proliferation. Tumor sections were stained for PCNA to reveal tumor cell proliferation in (A) HeyA8 model and (B) SKOV3 ip1 model. PCNA positive cells were counted and graphed. *p < 0.05 compared to vehicle controls. †p < 0.05 compared to bevacizumab alone. Images were taken at original magnification x400 for (A) and x200 for (B).
