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. Author manuscript; available in PMC: 2011 Aug 14.
Published in final edited form as: Antiviral Res. 2008 Jun 20;80(2):114–123. doi: 10.1016/j.antiviral.2008.05.010

Table I.

The data are reported as an average of at least three independent experiments.

Inhibitor Structure Targeted
Activity		 CC50 on
BSC-1a
(μM)		 IC50b (μM) TIc
VV HSV-2 VV HSV-2
123526 graphic file with name nihms-76527-t0007.jpg Processivity > 200 47.5± 2.6 34.8± 1.4 > 4.2 > 5.7
124808 graphic file with name nihms-76527-t0008.jpg Processivity > 200 > 200 33.1± 1.4 - > 6
55636
Fentichlor 		graphic file with name nihms-76527-t0009.jpg DNA
Polymerase		 > 200 5.7± 0.3 2.4± 1.7 > 40 > 100
69343
Tetracycline 		graphic file with name nihms-76527-t0010.jpg DNA
Polymerase		 > 200 > 200 47.5± 1.3 - > 4.2
Cidofovir graphic file with name nihms-76527-t0011.jpg DNA
Polymerase		 > 200 4 1.1± 2.1 > 50 > 182
a

Concentration at which compound is 50% cytotoxic

b

Concentration at which compound reduced plaques by 50%

c

Ratio of CC50 to IC50